Those hoping to uncover new science may feel disheartened if they struggle with inadequate tools and doubt that more capable tools are within reach. Until recently, such was the case in proteomics.

How mutations impact protein stability and structure dynamics is crucial for understanding the molecular mechanism of the disease and the targeted drug design. However, probing the molecular details ...

Four recent breakthroughs in proteomics that are changing the way we sequence, synthesize and discover proteins.

Proteins are vital to living systems. They build and repair tissues, act as enzymes to speed chemical reactions, regulate hormones and transport nutrients—all of which are important for developing ...

An illustration of an antibody disrupting the binding between a virus particle and a receptor on the edge of a membrane. A drug (orange) blocks the SARS-CoV-2 virus (gold sphere with white protruding ...

Just how far mass spectrometry—the use of tools measuring the mass-to-charge ratio (m/z) of one or more molecules present in a sample—has progressed over the past century can be seen in a new exhibit ...

Proteomics is the large-scale study of proteins, particularly their structures and functions. It involves the systematic identification, quantification, and analysis of the entire protein complement ...

Saint Louis University’s Protein Core is a shared-use core facility that supports expression, purification and analysis of reagent and preclinical proteins. The core provides instrumentation and ...