Chief among these is accurately and reproducibly mimicking natural post-translational modifications. Identifying and characterizing such modifications impact half-life, quality, cost, and potential ...
Post-translational modifications (PTMs) play a key role in dynamic cellular processes, regulating gene expression, protein activity, localization, and degradation, as well as protein interaction.
An epigenetic sensor uses a 21st amino acid to illuminate protein dynamics in real time to observe changes within cells.
Lactylation, a recently identified post-translational modification, has emerged as important for immune regulation, tissue repair, cancer cell metabolism, and now, potentially, Alzheimer’s disease. In ...
A team of researchers at the University of Liverpool, working in collaboration with the Mechanobiology Institute at the ...
This case study demonstrates how advanced NMR spectroscopy enables high-resolution structural characterization of exenatide.
Sir2, an enzyme belonging to sirtuins, has been shown to be involved in the deacetylation of proteins. Researchers from the ...
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