Chief among these is accurately and reproducibly mimicking natural post-translational modifications. Identifying and characterizing such modifications impact half-life, quality, cost, and potential ...
One of the main goals of proteomics is to unravel the many modifications important for biological activity. Post-translational modifications (PTMs) extend the range of protein function by attaching it ...
Post-translational modifications (PTMs) play a key role in dynamic cellular processes, regulating gene expression, protein activity, localization, and degradation, as well as protein interaction.
Pharmaceutical Technology on MSN
New protein manufacturing technologies likely to play key role in “five to ten years”
Eleva’s CEO says CHO cell line alternatives could become common as large molecule drugs become complex and harder to produce ...
Lactylation, a recently identified post-translational modification, has emerged as important for immune regulation, tissue repair, cancer cell metabolism, and now, potentially, Alzheimer’s disease. In ...
This case study demonstrates how advanced NMR spectroscopy enables high-resolution structural characterization of exenatide.
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