Chief among these is accurately and reproducibly mimicking natural post-translational modifications. Identifying and characterizing such modifications impact half-life, quality, cost, and potential ...
An epigenetic sensor uses a 21st amino acid to illuminate protein dynamics in real time to observe changes within cells.
Post-translational modifications (PTMs) play a key role in dynamic cellular processes, regulating gene expression, protein activity, localization, and degradation, as well as protein interaction.
Lactylation, a recently identified post-translational modification, has emerged as important for immune regulation, tissue repair, cancer cell metabolism, and now, potentially, Alzheimer’s disease. In ...
This valuable work provides new insights into the role of lysine acetylation of alpha-synuclein, the protein involved in Parkinson's Disease. The evidence is mostly solid, but the claims around the ...
AZoSensors on MSN
Self-sufficient Cells Light Up Enzyme Activity from Within
Autonomous cells producing acetyl-lysine offer a novel platform for real-time monitoring of enzyme activity, enhancing understanding of protein modifications.
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