Figure 1: LSD1 interacts with p53. Because LSD1 does not regulate the activity of p53 in BJ-DNp53 cells in which the DNA-binding ability of p53 is impaired, we reasoned that LSD1 might affect the ...

Scientists have recently shed some light on exactly why elephants, one of the biggest animals on the planet, paradoxically experience unusually low rates of cancer. The research found these remarkable ...

Scientists at Oregon State University say they have discovered a genetic function that helps the p53 tumor suppressor gene carry out its function and prevent cancer. Finding ways to maintain or ...

The most commonly mutated gene in cancer, p53, works by shifting cell metabolism in a way that alters a cell’s identity, researchers at the Sloan Kettering Institute have discovered. More than 50% of ...

CLN-049’s anti-leukaemic impact was observed regardless of FLT3 status, which is the most commonly mutated protein in AML.

St. Jude Children's Research Hospital scientists identified a promising combination approach to treat a rare, but ...

Scientists call it Peto's paradox: cancer is caused by gene mutations that accumulate in cells over time, yet long-lived animals that have lots of cells, such as elephants and whales, hardly ever get ...

December 16, 2025) St. Jude Children's Research Hospital scientists identified a promising combination approach to treat a ...

A single sperm donor who carries a rare cancer-causing genetic mutation has fathered at least 197 children across 14 ...

When cell division (mitosis) takes too long, it can be a sign that something is wrong with the cells, for example, DNA damage or chromosomal instability. That's why our cells come with an innate ...