The authors set out to answer a simple question. Do all chromosomes have the same chance of being mis-segregated during cell division? To address this, Klaasen and colleagues turned to several types ...

Using a new CRISPR-based technique, researchers are examining how the position of DNA within the nucleus affects gene expression and cell function. The nucleus of a cell has something in common with a ...

The cell nucleus is the site of many important biological functions of the eukaryotic cell. These processes include transcription, replication, splicing and ribosome biogenesis. The effect of these ...