Nitrofurantoin remains a first-line agent for uncomplicated urinary tract infections owing to its broad spectrum and multifaceted mode of action. As a prodrug, it undergoes intracellular reduction by ...

The novel investigational oral antibiotic gepotidacin was efficacious and safe for the treatment of uncomplicated urinary tract infections, with activity against common uropathogens. Gepotidacin, a ...

Background: The antibiotic nitrofurantoin is commonly used to treat uncomplicated urinary tract infections. However, when this drug is used by patients with reduced kidney function, its urine ...

The U.S. Food and Drug Administration just approved the first new antibiotic to treat urinary tract infections in nearly three decades. UTIs are infections in any part of the urinary system and affect ...

PARIS — To date, studies of antibiotic course length for treating urinary tract infections in men have been patchy and retrospective. Through recent randomized trials, guidelines can now be based on ...

Wendy Cheng, PhD, MPH, discusses how the study on the efficacy of gepotidacin vs nitrofurantoin in a nitrofurantoin-resistant population (a pooled analysis of the EAGLE-2 and EAGLE-3 trials) aimed to ...

A bladder infection is inflammation or irritation of the bladder, typically caused by bacteria. Your doctor may also refer to this as cystitis or a urinary tract infection (UTI) in your bladder. This ...

Physical examination follows the patient history and includes checking vital signs to assess for fever, tachycardia, and tachypnea. Suprapubic and costovertebral angle tenderness is checked with ...

A collaborative study, which includes contributions from NDORMS researchers Adam Crowther and supervisor Dario Carugo, explores new ways to model bladder biology. Urinary tract infections (UTIs) ...

Learn how certain conditions, contraceptives, lifestyle factors, and more can cause recurrent urinary tract infections and ...