Nature

Functional synonymous mutations and their evolutionary consequences

In virtually every organism, the 20 amino acids that make up all proteins are encoded by 61 of the 64 possible triplet codons in DNA, with the remaining three codons serving as stop signs in protein ...
Phys.org

Mutations driving evolution are informed by the genome, not random, study suggests

A study published in the Proceedings of the National Academy of Sciences by scientists from Israel and Ghana shows that an evolutionarily significant mutation in the human APOL1 gene arises not ...
The New York Times

Nature Is Still Molding Human Genes, Study Finds

Some researchers hold that evolution hasn’t much altered humans in the past 10,000 years. A new analysis of ancient DNA indicates that natural selection continued to shape hundreds of genes. By Carl ...
Nature

Engineering immunogens that select for specific mutations in HIV broadly neutralizing antibodies

Vaccine development targeting rapidly evolving pathogens such as HIV-1 requires induction of broadly neutralizing antibodies (bnAbs) with conserved paratopes and ...