The Detroit Lions’ comeback efforts came up short as the Pittsburgh Steelers secured a 29-24 win, capped off by an offensive pass interference call on wide receiver Amon-Ra St. Brown.

The San Francisco 49ers have beaten the Indianapolis Colts 48-27 on “Monday Night Football” behind Brock Purdy ’s career-high five touchdown passes. Christian McCaffrey racked up 146 total scrimmage yards and caught two touchdowns, while George Kittle totaled seven receptions for 115 yards and a TD before leaving the game with an ankle injury.