Multivariate linear mixed models (mvLMMs) are powerful tools for testing associations between single-nucleotide polymorphisms and multiple correlated phenotypes while controlling for population ...
Mixed linear models are used to analyze data in many settings. These models have a multivariate normal formulation in most cases. The maximum likelihood estimator (MLE) or the residual MLE (REML) is ...
A mixed model is a flexible tool for joint modeling purposes, especially when the gathered data are unbalanced. However, computational problems due to the dimension of the joint covariance matrix of ...
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