Installing a CPU on the motherboard is a lot easier if you do ... enthusiast chips like the AMD Threadripper and Intel's Xeon ...
Xeon W series processors will be available to system integrators initially, but I expect boxed processors and motherboards will be available for the DIY crowd down the line as well.
Intel's high-core count Xeon Platinum 9200 processors are getting new support ... the latter of which are connected to the motherboard through a simplified power distribution board.