Microtubules are dynamic, tubular polymers composed of αβ-tubulin dimers that form an essential framework within eukaryotic cells. They orchestrate a wide range of cellular functions including ...

Cytoplasmic streaming is the persistent circulation of the fluid contents of large eukaryotic cells, driven by the action of molecular motors moving along cytoskeletal filaments, entraining fluid.

Like poles support a tent, microtubules—hollow cylindrical structures made of tubulin protein—support eukaryotic cells. But microtubules provide more than just mechanical strength; they help prepare ...

Plant growth and development are a genetically predetermined series of events but can change dramatically in response to environmental stimuli, involving perpetual pattern formation and reprogramming ...

Researchers have developed photoresponsive derivatives of the anticancer drug Taxol®, which allow light-based control of cytoskeleton dynamics in neurons. The agents can optically pattern cell ...

Proteins containing disordered domains perform many important cellular functions. My lab currently has two main projects, one to dissect the role of tubulin's C-terminal tail in microtubule structure ...

Actin filaments (F-actin) are key components of sarcomeres, the basic contractile units of skeletal muscle myofibrils. A crucial step during myofibril differentiation is the sequential exchange of ...