While off-label use may be permissible, contraindicated use still has a strong regulatory boundary as reinforced by FDA guidance finalized in 2025.

Please provide your email address to receive an email when new articles are posted on . About two-thirds of individuals with invalid medical waivers submitted personal conviction waivers to avoid ...

A batch of antiretroviral drug labels has been updated to include Contraindications with an antidepressant. The Food and Drug Administration (FDA) announced that the following antiretroviral drug ...

In a recent study published in JAMA Network Open, researchers examined the prevalence of contraindications to nirmatrelvir-ritonavir (Paxlovid) in hospitalized coronavirus disease 2019 (COVID-19) ...

The finding that patients with gout often harbor comorbidities that lead to contraindications to many of the available pharmacologic therapies for gout has been well described. However, the first ...