Researchers Sumika Kato, Takeo Kubo, and Taro Fukazawa of the University of Tokyo have discovered that c1qtnf3, a secreting ...

Researchers Sumika Kato, Takeo Kubo, and Taro Fukazawa of the University of Tokyo have discovered that c1qtnf3, a secreting factor, namely a protein ...

Macrophages can alternate between two states: an inflammatory state for fighting infection and a non-inflammatory state for ...

Acute kidney injury (AKI) is associated with a poor prognosis, and no effective treatment has been established to date. Understanding the mechanisms that prevent the progression of AKI is crucial. In ...

Macrophages and other immune cells are the natural frontline immune warriors of our body, defending the body against invading pathogens and cancer cells. Yet despite their innate "combat" capabilities ...

Monocyte-derived blood macrophages of untreated patients with Leishmania braziliensis or Leishmania mexicana amazonensis infections show anomalies in their nonspecific immune functions. Their ability ...

Even its name is a testament to how enigmatic the tingible macrophage has been. Tingible, which means stainable, certainly gives no clues to its functions – but was, at least, one thing that was known ...

Macrophage polarization is critical to inflammation and resolution of inflammation. We previously showed that high-mobility group box 1 (HMGB1) can engage receptor for advanced glycation end product ...