Loss-of-function (LOF) technologies are widely used across many model organisms and many fields. Although all LOF approaches have the shared goal of perturbing gene function, there are complex ...
In a recent Molecular Therapy: Nucleic Acids study, researchers demonstrate enhanced loss-of-function editing of clustered regularly interspaced short palindromic repeats (CRISPR)/CRISPR-associated ...
ATG 2.5 and 0.5 mg/kg reduces loss of β-cell function in young people with recent-onset type 1 diabetes. (HealthDay News) — Antithymocyte globulin (ATG) 2.5 and 0.5 mg/kg reduces loss of β-cell ...
Some studies have suggested that in people with type 2 diabetes, Roux-en-Y gastric bypass has therapeutic effects on metabolic function that are independent of weight loss. We evaluated metabolic ...