Finerenone, a nonsteroidal mineralocorticoid receptor antagonist, demonstrated consistent efficacy and safety regardless of diuretic type or dose and reduced overall diuretic requirements in patients ...
Loop diuretics are cornerstone therapies for the relief of congestion in patients with heart failure. By inhibiting the Na⁺‐K⁺‐2Cl⁻ cotransporter in the thick ascending limb of the loop of Henle, ...
Finerenone reduced heart failure events and cardiovascular deaths in patients with HFmrEF or HFpEF when used with diuretics. The study found finerenone reduced hypokalemia risk but increased ...
BARCELONA, Spain—Patients with heart failure (HF) who are predicted to have a high risk of diuretic resistance tend to fare worse no matter whether they wind up taking furosemide or torsemide, with ...
Semaglutide reduces the need for loop diuretic use and dose, and has positive effects on symptoms, physical limitations, and body weight in patients with heart failure with preserved ejection fraction ...
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