One small compartment inside the nucleus has come into focus with regards to aging: the nucleolus. Its main job is simple and ...
A previously unknown type of DNA damage in the mitochondria, the tiny power plants inside our cells, could shed light on how ...
Scientists from Oxford's Radcliffe Department of Medicine have achieved the most detailed view yet of how DNA folds and ...
The laws of inheritance are quite unknown,” Charles Darwin acknowledged in 1859. The discovery of DNA’s shape altered how we ...
Much the way the caps on the ends of a shoelace prevent it from fraying, telomeres - regions of repetitive DNA sequences and a protein structure - protect the tips of chromosomes from damage. Every ...
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Bridge recombinases, optimized for human cells, enable massive programmable DNA rearrangements
For decades, gene-editing science has been limited to making small, precise edits to human DNA, akin to correcting typos in the genetic code. Arc Institute researchers are changing that paradigm with ...
DNA methylation is a key epigenome component that helps dictate how genes are expressed, contributing to normal cell and tissue differentiation during development, as well as the process of biological ...
Human embryos have been developed from eggs given the DNA of adult skin cells – a feat that had previously been achieved in mice. This could one day provide a way for same-sex couples or women with ...
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