This course has been approved by the Royal Society of Chemistry for purposes of Continuing Professional Development (CPD). What will you learn on this course? This is a perfect introduction for ...

The author describes how liquid chromatography-mass spectrometry works and explains some of its advantages and disadvantages, particularly compared to high-performance liquid chromatography. Within ...

The quality of data derived from MS can be enhanced by imposing a parameter called selected ion monitoring (SIM), which is highly sensitive and allows quantitative analysis that circumvents effects of ...

Liquid chromatography - mass spectrometry (LC-MS) combines two approaches to separate and identify molecules or compounds present in a sample. High performance liquid chromatography (HPLC) separates ...

LC-MS/MS has been increasingly adopted by clinical laboratories due to the potential it has for increased sensitivity and specificity over more commonly used analytical techniques. However, ...

This live, instructor-led training course provides an introduction to the fundamentals of LC-MS mass spectral interpretation. The course teaches how to obtain high quality mass spectra, simple ...

This is the final article in this series discussing HPLC oligonucleotide separations. This article will discuss LC/MS analysis of failure sequences, phosphorothioate modified siRNAs, CpG methylated ...

Modern SFC instruments show enhanced robustness and sensitivity, expanding their use beyond low-polarity compounds and into regulated environments. Thermo Fisher's Chromeleon 7.4 software enhances lab ...

Figure 1. A schematic representation of a lipid nanoparticle encapsulating mRNA. As this new form of biotechnology makes a leap of progress, so too do the analytical approaches supporting its ...

New users of the LC/MS laboratory and Sample Preparation Lab are required to engage in hands-on orientation to facility operations (e.g., laboratory access, scheduling, general use of equipment, ...