Credit: FDA. The FDA has received reports of tranexamic acid injection being erroneously administered intrathecally in the perioperative setting instead of the intended intrathecal anesthetic (eg, ...

A novel indwelling subcutaneous intrathecal catheter circumvented the complex spine anatomy of patients with spinal muscular atrophy (SMA), a challenge when giving nusinersen via intrathecal injection ...

Glycine, taurine, or muscimol was injected with bicuculline into the cistern magna or the lumbar subarachnoidal space in ICR mice. The effects on bicuculline-induced allodynia in a touch-evoked ...

Reports of pump failure, dosing errors, as well as other possible safety issues have prompted the Agency to issue the alert to make prescribers aware of the dangers associated with using medications ...

Heitor Medeiros, MD, and A. Sassan Sabouri, MD, of the Department of Anesthesia, Critical Care and Pain Medicine at Massachusetts General Hospital, are the lead and corresponding authors, respectively ...

THE neurologic manifestations of Central-nervous-system involvement in acute leukemia have been very well described. 1–7 Although involvement of the brain is not rare 7,8 greater emphasis has been ...

The basis for this interest derives primarily from two retrospective epidemiologic studies in the anesthesia literature suggesting significant differences in cancer recurrence dependent upon the ...

In a recent study published in Nanomedicine: Nanotechnology, Biology and Medicine, researchers evaluated the biodistribution of cannabidiol (CBD) emulsion and nanoparticles in the central nervous ...

The choice of which drug or combination of drugs, via what route, and in what manner remains a concern for the clinician. In choosing the dose and volume of local anesthetic for epidural labor ...

Postoperative shivering is a common and distressing complication following general and regional anesthesia. It arises from impaired thermoregulation and heat redistribution, manifesting as involuntary ...