Intermediate filaments (IFs) are critical parts of the structure of cells. They are essential for both normal tissue structure and function. Enabling cells to withstand the stretch and pressure on the ...

Biologists have found a unique version of a filament-forming protein in human cells that insects lack. Providing structural support and protection against such conditions as blistering, cataracts and ...

Just as the skeleton and muscles move the human body and hold its shape, all the cells of the body are stabilised and moved by a cellular skeleton. Unlike our skeleton, this cellular skeleton is a ...

The Journal of Cell Biology (JCB) is a not-for-profit publication, edited by scientists, and a leading life sciences journal. The JCB publishes papers on all aspects of cellular structure and function ...

Maintaining the shape of the cell, creating proper internal structure, guiding organelles and pulling chromosomes apart during mitosis are some of the important functions of the cytoskeleton. The ...

Glial Fibrillary Acidic Protein (GFAP) is a class-III intermediate filament that is mostly produced in astrocytic glial cells in the central nervous system. Astrocytes have important functions in ...

A number of spontaneous mutations in GFAP, encoding an astrocyte-specific intermediate filament protein, causes a neurodegenerative disease. It seems probable that these mutations effect gain of ...

The antigen recognized by the E/C8-monoclonal antibody is expressed in various avian embryonic cell types known also to express neurofilament (NF) immunoreactivity. To determine whether the ...

PhD defence: Tangled yet in tune: Orchestrating the dynamics of microtubules, vimentin and endoplasmic reticulum PLEASE NOTE: If a candidate gives a layman's talk, the livestream will start fifteen ...

Cancer cell vascular invasion is a crucial step in the malignant progression toward metastasis. Here we used a genome-wide RNA interference screen with E0771 mammary cancer cells to uncover drivers of ...