In a recent study posted to the bioRxiv* preprint server, researchers assessed the roles of the interferon (IFN) regulatory factors (IRFs): IRF1, IRF3, and IRF7 in infections by human coronaviruses ...

Treatment of COVID-19 with interferon beta-1b — even for just a few days, a much shorter period than is commonly used for maintenance in multiple sclerosis (MS), for example — is associated with ...

Over the past 35 years, interferons have been explored in various formulations for the management of Philadelphia chromosome–negative myeloproliferative neoplasms (MPNs), such as essential ...

An experimental COVID-19 antiviral appears to be effective at preventing hospitalizations without some of the downsides of other treatments. A study appearing Wednesday in The New England Journal of ...

Researchers in Germany have discovered that age-dependent impairments in antiviral interferon proteins underlie the increased susceptibility of older patients to severe COVID-19. The study, published ...

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Whether combined treatment with recombinant interferon beta-1b and lopinavir–ritonavir reduces mortality among patients hospitalized with Middle East respiratory syndrome (MERS) is unclear. We ...

Inhaled interferon-gamma may be an effective treatment for idiopathic pulmonary fibrosis (IPF), a chronic and progressive form of lung disease caused by excessive formation of fibrotic, or scar tissue ...

In a recent study published in The Journal of Infectious Diseases, researchers assess the proportion of interferon (IFN) autoantibodies in long-coronavirus disease (COVID) patients. Study: Low ...

In Part I of this article, which appeared in the January 2022 issue of GEN, William A. Haseltine, PhD, discussed findings that can help us understand why some people resist COVID-19 more effectively ...