A research group at Nagoya University in Japan has successfully developed an ultrafast and simple synthetic method for producing indole derivatives. Their findings are expected to make drug production ...

Scientists have achieved a new feat in molecular editing by swapping carbon for nitrogen, enabling the direct conversion of indoles into benzimidazoles. This simple switch in a one-pot method offers a ...

Indole is a ubiquitous nitrogen‐containing aromatic compound that acts both as an environmental pollutant and as a biological signalling molecule. Its inherent recalcitrance demands efficient ...

The development of drugs through chemical modifications of naturally occurring indole alkaloids has emerged as an attractive research area. However, due to their reactivity, the selective ...

A cost-effective copper-catalyzed reaction enables selective modification at the C5 position of the indole ring, a backbone for pharmaceutical compounds. Indoles, which form the backbone of many ...

Indole, a molecule made up of a six-membered benzene ring fused to a five-membered ring containing nitrogen, forms the core structure of many biologically active compounds. Derivatives of indole, ...

A new chemical reaction pioneered by researchers from the University of Toronto (Toronto, ON, Canada) simplifies the production process for indole rings, a basic molecular frameworks commonly used in ...

You’ve undoubtedly smelled indole. Perfumers add it to flowery fragrances, but it’s also added to chocolates, coffees, and fruity-flavored sweets. That doesn’t sound bad—until you learn that ...

Plants make a surprising intermediate en route to quinine and cinchonidine ...

The proposed method is simple, mild, fast, and produces high yields, with the potential to inspire the development of new drugs and agrochemicals. Indolo[2,3-a]quinolizidine is a common structural ...