A method for arrayed CRISPRi screening in organoids enables the investigation of morphogenesis in human stem cell-derived tissues, revealing the roles of ZIC2, SOX11, and ZNF521 in neural tube closure ...
The US Food and Drug Administration (FDA) mandated folic acid fortification of all enriched cereal grains in 1996, and this regulation resulted in a reduction of neural tube defect (NTD)–affected ...
Neural tube defects (NTDs) rank as the second most prevalent congenital malformation in humans, impacting the central nervous system development in approximately 1 in every 1,000 live births. Over 300 ...
Quails are small, plump birds that scurry through grasslands on foot rather than take to the skies. Unexpectedly, studying these ground-dwellers has helped scientists uncover clues about a type of ...
Analysis of U.S. survey data showed that two-thirds of reproductive age women had one or more modifiable risk factors for birth defects. Common risk factors included obesity, folate concentrations ...
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