The DNA packed inside every human cell contains instructions for life, written in billions of letters of genetic code. Every time a cell divides, the complete code, divided among 46 chromosomes, must ...
When cells proliferate, genomic DNA is precisely duplicated once per cell cycle. Abnormalities in this DNA replication process can cause alterations in genomic DNA, promoting cellular ageing, cancer, ...
Transposons, DNA sequences that can self-replicate and move (jump) throughout the genome, are widespread and can affect cell ...
The MCM helicase is broadly bound across the genome, and its phosphorylation is antagonistically regulated by the kinase DDK and the phosphatase RIF1–PP1. TRESLIN–MTBP recognises the phosphorylated ...
Researchers have found that the way DNA is packaged in cells can directly impact how fast DNA itself is copied during cell division. They discovered that DNA packaging sends signals through an unusual ...
Single-cell analysis helps uncover how the BK virus replicates, opening the door to new drug targets. BK polyomavirus (BKPyV) is a major cause of kidney transplant failure. Without a complete ...
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