This important study, which tackles the challenge of analyzing genome integrity and instability in unicellular pathogens by introducing a novel single-cell genomics approach, presents compelling ...

Pioneering research utilizes high-throughput single-cell sequencing to demystify the microbial universe within activated sludge, a cornerstone of wastewater treatment. This study has unearthed a ...

On January 21st, the Thalassemia International Federation (TIF) and BGI Genomics jointly hosted an educational webinar focused on thalassemia prevention in high-prevalence regions. The event featured ...

The landscape of next-generation sequencing (NGS) continues to be defined by astonishing technological progress. We continue ...

Misfolded proteins can appear as small aggregates, soluble monomers, or large insoluble inclusion bodies. While the fundamental biophysical mechanisms that cause cytotoxicity are not fully understood, ...

The low-pass whole genome sequencing technique involves sequencing each genome base several times. It is increasingly popular in agricultural studies, as agricultural genomes typically have a broader ...

Preliminary results from a first-in-human trial of AMT-116, a topoisomerase I inhibitor containing antibody-drug conjugate (ADC), in patients with advanced solid tumors. A novel oral microtubule ...

Validated next-generation sequencing soon will become necessary in ensuring the safety and efficacy of cell and gene ...

This image illustrates the typical steps in next-generation sequencing (excluding single-molecule sequencing methods). The process begins with isolating genomic DNA (a) and breaking it into short ...