The drug, delivered by EMS as a single injection, improved infarct-related patency at cath lab arrival and 30-day clinical ...

Retrospective analyses in non-randomised cohorts suggest that regimens containing fludarabine/Ara C and/or idarubicin/ara C may be more effective than daunorubicin/AraC (DA)-containing regimens in ...

To investigate the effects of nitric oxide (NO) donors on the function and expression of P-glycoprotein (P-gp) in Caco-2 cells. Exposure of Caco-2 cells to 0.1 or 2 mmol/L of sodium nitroprusside (SNP ...

Severe acute respiratory syndrome virus 2 (SARS-CoV-2), the causative agent of coronavirus disease 19 (COVID-19), uses its spike (S) glycoprotein to enter host cells. The S glycoprotein consists of ...

Thanks to a decadelong synthetic push, chemists finally have access to a homogeneous version of the blood-cell-producing glycoprotein erythropoietin (EPO). The product carries carbohydrates at the ...

When the Ebola virus infects a host cell, the first thing it does is attach itself to the cell using a glycoprotein. A newly obtained structure of that glycoprotein—the highest resolution one to ...

Patients with nonvalvular atrial fibrillation and normal kidney function had increased bleeding risk with dabigatran when used alongside P-glycoprotein inhibitors diltiazem and verapamil, according to ...

SLC35G3-mediated UDP-GlcNAc transport is essential for proper sperm glycoprotein formation and male fertility.

This is a preview. Log in through your library . Abstract Glycoprotein (GP) V is a major substrate cleaved by the protease thrombin during thrombin-induced platelet activation. Previous analysis of ...

Replacing a step in sample preparation with an automated approach improves both method precision and productivity. Glycosylation is a critical quality attribute (CQA) for therapeutic proteins, ...

WEST LAFAYETTE, Ind. – For scientists working to develop gene transfer and gene therapies, finding an ideal carrier system is half the battle. Current systems are often difficult to produce, and may ...