An integrin mutation impairs skin T cell migration, enabling HPV proliferation that causes warts and lesions in a rare genetic dermatological condition.

A single genetic “switch” may be the secret to how the body’s cleanup crew grows up and keeps our organs running smoothly.

To further the quantitative understanding of cellular decision making, Dr. Gregory Reeves and his team in the chemical engineering department have worked to interpret how a transcription factor ...

The genetic network of BTB zinc finger transcription factors and Eip93F is crucial for Kenyon cell identity regulation and neuronal function acquisition in the construction of Drosophila mushroom ...

Our immune systems function by employing two separate responses when in contact with disease. The first is the innate immune system, which aids in monitoring for infection throughout the body. Innate ...

Scientists have identified how specific genetic changes function in cells to influence disease risk and other human health ...

Researchers at the School of Biological Sciences of The University of Hong Kong (HKU) have uncovered how eukaryotic cells can control gene activity even after losing one of their major gene-regulatory ...

CAR T cells are patient-derived, genetically engineered immune cells. They are "living drugs" and constitute a milestone in modern medicine. Equipping T cells, a key cell type of the immune system, ...

In modern functional genomics, understanding how specific genes control cellular behavior requires both targeted intervention and high-resolution analysis. That’s where Perturb-Seq comes in—a method ...

Researchers at the Weill Institute for Cell and Molecular Biology have uncovered new evidence that two major types of gene-controlling DNA sequences, promoters and enhancers, operate with a shared ...