Gene regulation is the process by which cells control the expression of their genes, determining when, where, and to what extent each gene is expressed. It is a fundamental mechanism that allows cells ...

Much of the phenotypic variation that is observed within and between species is the result of differences in gene regulation: specifically when, where and how much the genes are expressed. Given the ...

The central focus of exploring regulatory elements in mRNA has been on sequence-specific RNA-binding proteins (RBPs) that influence mRNA stability, translation, and splicing. On the other hand, some ...

Controlling gene expression is essential to growth, development, and sustained life. This requires regulating the spacial, temporal, and developmental expression of genes in a wide diversity of cell ...

Recent work reported in Nature highlighted the importance of methylation on messenger RNA (mRNA). Methyl tags that are added to mRNA can have a dramatic impact on the fate of mRNA transcripts. Now an ...

A research team has identified the core gene expression networks regulated by key proteins that fundamentally drive phenomena such as cancer development, metastasis, tissue differentiation from stem ...

Your skin cells are clearly different from your brain cells even though they both develop in the same person and carry the same genes. They are different because each cell type expresses a particular ...

Research will focus on the genome-wide identification of microexons to advance the knowledge on gene functions.

In biology classrooms, we often learn that genes are transcribed into mRNA, which is then translated into proteins—a tidy, linear process. But gene expression in living cells is far more intricate, ...

Although HPVs do express some unspliced mRNAs (Figure 2), most HPV mRNAs are the products of constitutive and alternative splicing. Constitutive splicing is where every intron in the primary RNA ...

One cannot make these kinds of statements based on relative measurements." Hwa believes this research will reframe how gene expression and regulation is taught in biology textbooks and classrooms ...