CTCF is widely recognized for its essential role in mediating chromatin loops to regulate gene expression, particularly by modulating enhancer-promoter (EP) interactions. However, acute depletion of ...
Senataxin (SETX) is an RNA/DNA helicase which catalyzes the resolution of R- loops, inherent byproducts of transcription consisting of an RNA:DNA hybrid and a displaced single-stranded DNA. Gain or ...
The alternative text for this image may have been generated using AI. The natural prevalence of R-loops and G4s at telomeres and promoters can facilitate genomic maintenance of these features. At ...
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