A New York Times health reporter explains what clinical trials are, why they are important and how they can help inform us.

The authors examine the origin, benefits, and challenges of pragmatic clinical trials to assess the ultimate value of this research design. Pragmatic clinical trials (PCTs), which test if and how ...

The rapid development and integration of artificial intelligence (AI), including predictive, generative, and emerging agentic ...

There is an explosion of innovation in drug development. In 2023, the FDA approved 55 novel drugs. There were five approved gene therapies for rare diseases, including the first-ever FDA-approved ...

The SWOG S2302 Pragmatica-Lung trial, which broke new ground with its streamlined pragmatic design, unusually broad eligibility criteria, and reduced data collection, has quickly answered its primary ...

Correspondence to Dr Eli Puterman, The University of British Columbia, Vancouver, BC V6T 1Z4, Canada; eli.puterman{at}ubc.ca Background The number of adults across the globe with significant ...

Laura A. B. Wilson receives funding from the Australian Research Council. Shinichi Nakagawa receives funding from the Australian Research Council. Compared to men, we know much less about how women ...