The authors examine the origin, benefits, and challenges of pragmatic clinical trials to assess the ultimate value of this research design. Pragmatic clinical trials (PCTs), which test if and how ...
The rapid development and integration of artificial intelligence (AI), including predictive, generative, and emerging agentic ...
A New York Times health reporter explains what clinical trials are, why they are important and how they can help inform us.
There is an explosion of innovation in drug development. In 2023, the FDA approved 55 novel drugs. There were five approved gene therapies for rare diseases, including the first-ever FDA-approved ...
The US’s National Cancer Institute (NCI) has helped launch a phase 3 clinical trial, the Pragmatica-Lung Study, investigating the use of a two-drug treatment for people with advanced (stage 4) ...
Pragmatic clinical trials can use EHR data to help cut costs and human effort associated with randomized clinical trials, according to commentary published in JAMA Network Open on Dec. 28. The ...
Pragmatic trials may offer one way to increase minority populations in multiple sclerosis (MS) studies, investigators for the DELIVER-MS trial suggested. Race and ethnicity did not appear to influence ...
PCORI places a high level of emphasis on using optimal methodology for patient-centered CER. PCORI applications need to address (or justify not addressing) 64 different methodology standards. These ...
The Clinical Trials Office at Saint Louis University supports innovative clinical investigative research at the SLU School of Medicine. Our office provides clinical trial management for ...
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