This method uses polymer modifications to tune enzyme activity for increased solubility in non-native solvents. Tuning the miscibility of enzymes in non-native solvent environments has important ...

Sanofi has developed a simpler way to create site-specific antibody-to-mannose-6-phosphate (M6P) conjugates that eliminates the need for enzyme remodeling. This more straightforward method makes M6P ...

The peptidases can break bonds between specific D- and L-amino acids, filling a gap in the toolbox for natural products ...

Archaeosine is synthesized via three steps in tRNA. ArcS, the second-step enzyme, transfers a lysine to preQ 0, which is introduced into tRNA by ArcTGT, the first-step enzyme. The resultant preQ 0-Lys ...

Proteins are the workers in a cell and, as the "basic element of life", are responsible for the most widely varying metabolic processes. In plants, for example, they take on an important function in ...

A team has modeled improving photosynthesis through enzyme modification and simulated soybean growth with realistic climate conditions, determining to what extent the improvements in photosynthesis ...

After a long search, RIKEN researchers have identified an enzyme crucial for keeping lipid-linked sugar chains in check in yeast cells. This finding, published in the Journal of Cell Biology, reveals ...

An analysis of an unusual enzyme could result in a new generation of antimicrobial medicines to counter antibiotic resistance. Key details in the enzyme-driven biosynthesis of a natural molecule with ...