Chemical structure for thiamine pyrophosphate and protein structure of transketolase. Thiamine pyrophosphate cofactor in yellow and xylulose 5-phosphate substrate in black. Credit: Thomas ...

Researchers participating in the Enzyme Function Initiative (EFI) have used a computationally rich metabolite-docking strategy to sift through a protein’s potential metabolic partners and predict its ...

Researchers from Tokyo Metropolitan University have developed a new structure determination method using Nuclear Magnetic ...

UPTON, NY - Scientists have long thought that individual enzymes have specific, single jobs dependent on their molecular shape. According to this premise, enzymes could only evolve to perform new ...

While E. coli is one of the most studied organisms, the function of 30% of proteins that make up E. coli has not yet been clearly revealed. For this, an artificial intelligence was used to discover ...

Cytochrome P450 enzymes constitute a superfamily of haem-containing proteins that catalyse the oxidation of a wide range of exogenous and endogenous compounds. Their function is fundamental to the ...

Annotations of enzyme function provide critical starting points for generating and testing biological hypotheses, but the quality of functional annotations is hindered by uncertain assignments for ...

Iridoids are a widespread and evolutionarily ancient class of plant secondary metabolites belonging to the terpenes. They ...

As the world’s population increases and squeezes limited resources, everyone will have to do more with less – and one tool that can help with this is enzymes, such as those made by Novozymes. At IFT’s ...

Patients with lupus are at increased risk of heart disease. Exposing endothelial cells -- known to protect against heart disease, in part by producing nitric oxide -- to the serum of patients with ...

A new study in mice has made a possible breakthrough in Alzheimer’s research. The team of researchers at the Cleveland Clinic has noted that deleting a single enzyme can reverse the deposition of ...

Scientists have discovered a new function in a plant enzyme that could inspire the design of new chemical catalysts. The enzyme catalyzes, or initiates, one of the cornerstone chemical reactions ...