Specific glycans attached to the GnT-IVa and GnT-IVb can bind to the enzyme’s ligand-binding site, interfering with recognition and binding to the glycosylation proteins’ normal glycoprotein ...

Clascoterone (cortexolone 17α-propionate) is a first-in-class topical anti-androgen approved in 2020 for the treatment of acne in patients aged 12 years and older. It works by blocking androgen ...

Years of toil in the laboratory have revealed how a marine bacterium makes a potent anti-cancer molecule. The anti-cancer molecule salinosporamide A, also called Marizomb, is in Phase III clinical ...

As demand intensifies for "green chemistry" standards across the pharmaceutical and chemical industries, Creative Enzymes—a leading global enzyme technology service provider—today announced the ...

A new study finds enhanced activity of a specific enzyme drives spinocerebellar ataxia type 14, which suggests inhibiting the enzyme may have therapeutic potential. pinocerebellar ataxias are a group ...

Macrolides are an important class of antibiotics that includes drugs such as azithromycin and erythromycin, which are widely used to treat a range of infections, including pneumonia and skin ...

Here's what enzymes are, what they do and how you'll know if you are ever low on them.