Mitochondrial transcription elongation factor maintains the balance between transcription and replication of mitochondrial DNA offering insights into potential treatments for mitochondrial disease and ...

As imaging tools continue to get more sophisticated, researchers have been able to actually watch biological processes as they are happening in live cells. Scientists have now visualized loops of DNA ...

A team of researchers has found that transcription factors have a tendency to bind strongly to 'mismatched' sections of DNA, i.e. sections of the genome that were not copied correctly. The strong ...

Scientists successfully induced gene expression from a DNA and evolution through continuous replication extracellularly using cell-free materials alone for the first time. By adding the genes ...

Mitochondrial deoxyribonucleic acid (mtDNA) is essential for cellular energy production and overall cell function.

A cell protein previously believed only to provide a scaffolding for DNA has also been shown to directly influence DNA transcription into RNA – the first step of the process by which an organism's ...

When the molecular machinery in our cells gets to work transcribing the genetic information encoded in DNA into messenger RNA (mRNA), it pauses shortly after starting. Known as promoter-proximal ...

This transcript has been edited for clarity. For more episodes, download the Medscape app or subscribe to the podcast on Apple Podcasts, Spotify, or your preferred podcast provider. Dr Liu is a ...

A detailed picture of what happens when DNA transcription is paused early in the process has been obtained by structural biologists at RIKEN. This could inform the development of new therapies.