Figure 1: Recognition and repair of O 6-alkylguanines by AGT. Figure 3: Minor groove binding, nucleotide flipping and O 6-akylguanine recognition by AGT. The directional repair effect for ssDNA is not ...
32 P-label is introduced by incoming dGT 32 P molecule. The arrows indicate the sites of enzymatic hydrolysis. The bases of the template DNA strand are designated as clear boxes, and the bases in the ...
Quality control of genetic material is a function conserved in all living organisms. DNA suffers from many environmental stresses, including attacks by reactive oxygen species, radiation, UV light, ...
Anyone who studied a little genetics in high school has heard of adenine, thymine, guanine and cytosine -- the A, T, G and C that make up the DNA code. But those are not the whole story. The rise of ...
DNA, a molecule famous for storing the genetic blueprints for all living things, can do other things as well. In a new paper, researchers describe how tailored single strands of DNA can be used to ...
Understanding how cells turn genes on and off is one of biology's most enduring mysteries. Now, a new technology developed by chemist Brian Liau and his collaborators at Harvard offers an ...
Inside every cell, a finely tuned metabolic network determines when to build, recycle, or stop producing essential molecules.
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