The DNA in the cell nuclei of higher organisms is tightly coiled around protein complexes called nucleosomes, which repress gene expression. Researchers in Germany have now developed a model that ...

An imaging method that reveals a much more diverse and flexible DNA-protein chromatin chain than previously thought has now been developed by researchers. The result suggests a nimbler structure to ...

Scientists have created an unprecedented 3-dimensional structural model of a key molecular "machine" known as the BAF complex, which modifies DNA architecture and is frequently mutated in cancer and ...

Eukaryotic genome stability relies on the presence of telomeres, specialized protein–DNA complexes that compose the very ends of the linear chromosomes 1. Telomeres form protective caps at the ends of ...

Erwin Chargaff's groundbreaking research, which showed that DNA base pairs had a complementary relationship, laid the foundation for James Watson's and Francis Crick's DNA model. When word spread that ...

In both physics and chemistry, the mesoscopic scale refers to the length scale on which the properties of a material or phenomenon can be studied, without entering into a discussion about the behavior ...

On February 28, 1953, James Watson and Francis Crick informally announced that they had discovered the double-helical structure of DNA. They soon reported their find more formally. On April 25, 1953, ...

Geneticist Sir Paul Nurse on the amazing breakthroughs that followed the discovery of DNA - and how it directly impacted his own family. Made by BBC Ideas in partnership with the Science Museum Group, ...