A cancer drug target already being investigated in clinical trials turns out to be doing something even more consequential ...

Discovery reshapes understanding of how tumor cells repair broken DNA, pointing toward more precise cancer therapies.

A team of cancer genomics scientists from The University of Manchester and The Institute of Cancer Research, London, ...

Millions of Americans take daily supplements—including nicotinamide mononucleotide (NMN), nicotinamide riboside (NR) and nicotinamide (NAM)—to ...

A new study shows that cancer damages its own DNA by pushing key genes to work too hard. Researchers found that the most powerful genetic "on switches" in cancer cells, called super-enhancers, drive ...

CDT1 inhibits the helicase activity of the MCM complex, thereby suppressing nascent strand synthesis in DNA replication in cultured human cells. This action results in fork collapse and DNA damage, ...

Oestrogen-induced DNA damage drives genomic instability in BRCA1 mutation cells, with dietary compounds showing protective potential.

New research has found that oestrogen-induced DNA damage in individuals carrying BRCA1 mutations may play a crucial role in the initiation of cancer, while also pointing to a potential dietary ...

A new fluorescent sensor is giving scientists an unprecedented view of how cells respond to DNA damage, capturing the repair process as it unfolds in real time. The tool, developed at Utrecht ...

VAPING is ‘likely’ to cause lung and mouth cancer, scientists fear. E-cigarettes have long been touted as a way to stop ...