THE myosin crossbridges which project from the thick filaments of striated muscle are known to bend and attach to the thin filaments in the absence of their enzymatic substrate, ATP 1. Huxley and ...

The research team developed a genetically engineered mouse model carrying a mutation (E3896A) in RyR1, which disrupts its calcium-binding site, effectively disabling CICR while preserving ...

This is a preview. Log in through your library . Abstract Particular thiols of the myosin subfragment 1 moieties of single glycerinated muscle fibers are covalently labeled with rhodamine. By using ...

The flow of water within a muscle fiber may dictate how quickly muscle can contract, according to a new study. The flow of water within a muscle fiber may dictate how quickly muscle can contract, ...

The contraction kinetics of calcium-activated skinned muscle fibers were studied after step decreases in load by means of a quickly responding recording system. The steady velocity at a given relative ...

Numerous motor and structural proteins compose a highly ordered structure known as the sarcomere, the basic unit of muscle contraction in heart and skeletal muscles. Sarcomeric myosin heavy chain ...