The model is based on the earlier discovery that the cell-cycle regulator Cdk1 is asymmetrically distributed in the oocyte cytoplasm, where it forms a concentration gradient that extends from the ...
Critical concentration gradient model is helpful in understanding the mechanism of Z-ring formation. The distribution of positive and negative regulators of Z-ring formation in cell is not random but ...
The potential to isolate and regulate the biodynamics of single cells is significant in drug design and screening. However, pre-existing experimental reports in single-cell drug screening must yet ...