Collections of small molecules are used routinely in high-throughput screens to find new drug leads. In fact, from 1999 to 2008, 45 of the 50 Food and Drug Administration approvals for first-in-class ...

Robots can help develop them ...

A major step toward simpler drug development has been taken at the University of Gothenburg. In a new study, researchers have developed stable boron-fluorine compounds that make it possible to ...

Chemists have synthesized a highly complex natural molecule through a new strategy of functionalizing normally inert carbon-hydrogen (C-H). The journal Science has published the breakthrough. Led by ...

A major step towards simpler drug development has been taken at the University of Gothenburg. In a new study, researchers ...

AI has fundamentally altered the feasibility of natural product discovery from fungal endophytes. Advances in genome sequencing, metabolomics, and systems biology have generated vast datasets, but ...

For the first time, MIT chemists have synthesized a fungal compound known as verticillin A, which was discovered more than 50 years ago and has shown potential as an anticancer agent. The compound has ...

Scientists report the first confirmed detection of thiepine, a complex sulfur-bearing molecule, in an interstellar cloud near the Milky Way’s center.

Hazardous materials responders across the country have a new way to look at hazmat chemistry: the "HazMat IQ" system, which lets responders see immediate application of the material to their response ...

Researchers at the Max Planck Institute for Extraterrestrial Physics (MPE), in collaboration with astrophysicists from the ...