In mantle cell lymphoma (MCL), an aggressive form of B-cell non-Hodgkin lymphoma, TP53 mutations are known to affect patients’ prognosis—but questions remain. What does the heterogeneity of TP53 ...
A study led by Aaron Hobbs, Ph.D., and Rachel Burge, Ph.D., at MUSC Hollings Cancer Center, reveals why a specific gene ...
The American Cancer Society estimates that over 80,000 individuals will be diagnosed with bladder cancer this year.
Believed to be caused by a mix of genetic and environmental factors, Parkinson’s disease is a chronic, progressive disease that affects the central nervous system, particularly the motor system, ...
Genetic mutations aren't always a bad thing. A groundbreaking new study suggests that mutations on a single gene may actually be beneficial when it comes to Alzheimer’s disease. For the study, Dr.
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How sickle cell changed human evolution

Sickle cell disease is caused by a single genetic mutation that alters the shape of red blood cells. While the condition causes severe pain and health complications, carriers gain resistance to ...
A new single-cell profiling technique has mapped pre-malignant gene mutations and their effects in solid tissues for the ...
Many people are familiar with histamine, a biological molecule that serves as a key driver of allergic reactions and other ...
Gene therapy has the potential to dramatically benefit patients with genetic blood disorders, but a small study on participants in a clinical trial for sickle cell disease suggests that a key process ...
A new study suggests a gene mutation could have a protective effect against Alzheimer's. The research looked specifically at blood stem cells, which live in the bone marrow and make different types of ...