In a global breakthrough published in Nature Genetics, researchers have successfully mapped the cells and genes that regulate ...

Skeletal stem cells (SSCs) are essential for bone development, homeostasis, and repair. Recent studies have identified distinct SSC populations in long bones, craniofacial bones, and spine. Techniques ...

Living cells contain a world of complex parts, which are constantly in motion. Many functions of these parts are still not fully understood, but likely harbor answers to many of our questions about ...

Glass bone disease is more than just a plot device in a movie, it's a real but very rare disorder that affects tens of ...

Rather than completely blocking all downstream signals, the peptide developed in this study focuses on inhibiting the activation of p38-MAPK. This is enough to downregulate the development of mature ...

Gain-of-function mutations in fibroblast growth factor receptor (FGFR) genes are known to cause a range of skeletal disorders, such as craniosynostosis and chondrodysplasia, which severely affect ...

New study identifies CAR3 as a key osteoblast protein promoting collagen mineralization, bone formation, and skeletal ...

Stem cells form the backbone of many cell-based therapies due to their unique properties, including the ability to self-renew and differentiate to many cell types. Multiple cell therapies deliver ...