Industry is adapting to the increasing complexity and poor solubility and bioavailability of molecules in the pipeline. Poor solubility and low bioavailability have hindered the development pipeline ...

When it comes to supplements, absorption matters just as much as the dosage. You could be taking the most potent multivitamin or mineral supplement, but if your body can’t absorb it properly, it won’t ...

I drink a full glass of milk every day and eat cheese, but still, I am deficient in calcium. I include iron-rich foods in my diet to meet my daily requirement of iron, but I am still anemic. It is ...

Want to improve the nutritional benefits of your favourite foods? You may need to start thinking about bioavailability… We all want to get the most out of the food we eat, but there’s much more to ...

Limited-sampling models for irinotecan pharmacokinetics-pharmacodynamics: prediction of biliary index and intestinal toxicity. Twenty-nine patients received oral EP (capsules, 50 to 150 mg/m2/d of E ...

Objective: Flavanones are polyphenols specific of citrus fruits, where they are present in high amounts. Although citrus fruits and juices are widely consumed in the world, little information has been ...

The randomized, open-label, crossover clinical study, led by Priyank Rathi, MD, was published in the science journal Phytomedicine Plus, last July. It evaluated the bioavailability in 16 healthy human ...

Why Iron Deficiency is a Concern? Iron is an essential mineral that carries out critical functions in the body. It is linked with oxygen transport in blood and muscle and its storage, hormone ...

Objective: To measure the bioavailability of selenium from cooked and raw fish in humans by estimating and comparing apparent absorption and retention of selenium in biosynthetically labelled fish ...

Although efforts have been made to improve solubility, many poorly soluble drugs still reach the market. Peter Nielsen discusses new developments in solubilisation technology, which could help those ...