This paper describes a method for a model-based analysis of clinical safety data called multivariate Bayesian logistic regression (MBLR). Parallel logistic regression models are fit to a set of ...

Adaptive clinical trials use algorithms to predict, during the study, patient outcomes and final study results. These predictions trigger interim decisions, such as early discontinuation of the trial, ...

Journal of the Royal Statistical Society. Series B (Statistical Methodology), Vol. 67, No. 2 (2005), pp. 219-234 (16 pages) Precise classification of tumours is critical for the diagnosis and ...