Tumor growth and metastasis require new blood ves-sel growth, a process called angiogenesis. There are many factors involved in the nor-mal growth and stabilization of new blood vessels. One of these, ...

Targeting sphingosine-1-phosphate receptors with the oral immunomodulator drug FTY720 (fingolimod) has demonstrated substantial efficacy in the treatment of multiple sclerosis. The drug is ...

Actelion's selective S1P1 receptor agonist moves into advanced clinical development in psoriasis - Phase IIb dose-finding study in multiple sclerosis already ongoing - Roche to leave S1P1 alliance ...