Patients with sickle cell anemia (SCA) and persistent albuminuria (PA) exhibited significantly higher levels of urinary angiotensinogen (AGT). “What we’re most excited about is that urinary ...

Angiotensinogen plays a key role in hypertension pathogenesis. Zilebesiran, an RNA interference therapeutic agent that inhibits angiotensinogen production, is being studied for hypertension treatment.

The renin–angiotensin system has an important function in the regulation of blood pressure as well as in pathophysiological processes in the central nervous system. We examined the effects of the ...