Adenosine diphosphate (ADP) or adenosine triphosphate (ATP)-containing important biological molecules can modify macromolecules like proteins and nucleic acids to alter their function in the cell.
Extracellular purine (ATP, ADP) and pyrimidine (UTP, UDP) nucleotides mediate their effects via P2 receptors (Ralevic and Burnstock, 1998). P2 receptors consist of ligand-gated intrinsic ion channels, ...
Researchers used a novel phosphate-activation reagent, 2-MeImIm-Cl, in an improved coupling reaction to increase the yield of ADP- or ATP-containing molecules. Unlike traditional reactions, the ...