In the wee hours of an October morning, David Baker, a protein biologist at the University of Washington (UW), received the most-awaited phone call in a scientist’s career. Halfway around the world, ...

Protein engineering is a powerful biotechnological process that focuses on creating new enzymes or proteins and improving the functions of existing ones by manipulating their natural macromolecular ...

Complex protein interactions at synapses are essential for memory formation in our brains, but the mechanisms behind these processes remain poorly understood. Now, researchers have developed a ...

University of Chicago alum John Jumper was awarded a share of the 2024 Nobel Prize in Chemistry on Oct. 9 for developing an AI model that predicts the complex folded structures of proteins. The Royal ...

The three-dimensional shape of a protein can be used to resolve deep, ancient evolutionary relationships in the tree of life, according to a study in Nature Communications. It is the first time ...

The proteins found in nature represent only a tiny fraction of the nearly limitless protein structures that could theoretically exist. By designing proteins de novo—from scratch—scientists can more ...

The intrinsically disordered proteins (IDPs) do not attain a stable secondary or tertiary structure and rapidly change their conformation, making structure prediction particularly challenging. These ...